Exhibition Of Genome Expression Pattern- A Research By Bio-Medicine

Bio-Medicine is a field of medical science that is concerned with the theories and research work required to be carried out in order to develop new methods for diagnosing various diseases and also the methods for treating them. A recent research in the field of biomedicine has led to the development of a system that can analyze the clusters from the DNA microarray hybridization in order to display the genome expression patterns.

The design of the system is such that it makes use of standard algorithms that can position the genes in the order of similarity in their expression patterns. Moreover in this system, graphs have been used to display the outputs. The graph plots the clustering and the fundamental expression data at the same time in such a manner that can easily help the biologists in the process of predicting newer theories and results.

During the research it was found that genes with similar functionalities can be grouped together effectively by making the clusters of the expression data of genes. Though this result was the outcome of an experiment performed on the budding yeast named Saccharomyces Cerevisiae, but the biologists believe that the same propensity is found in the human data as well. Thus the cellular processes' statuses can be easily indicated by the interpretation of the gene patterns found in the experiments conducted for studying the genome expression pattern.

The advancements in the algorithms used to arrange the genes in particular sequences have led to the characterization of the processes involved in Biology in even newer and better ways. The study has suggested that once the coding cycle of nearly every gene is understood, then the technology can make advancements towards the development of the systems that can provide even better discernment in the understanding of the underlying processes involved in the study of genome-wide expression patterns.

The most natural way of extracting the genome expression pattern information is to observe the extremities in a holistic genetics research approach. This observation can be easily made by taking two genes with different patterns in two different samples individually and examining them for a particular time period thereby giving them similar treatment under different conditions.

The basic method that has been developed till date for the study of genome expression pattern involves the grouping of the genes together as per the similarity in their expression patterns. This can be done by application of any of the similarity theorems available in mathematics. The "dot-product" theorem is generally used for conforming whether two genes can be stated as "co-expressed" or not. But the problem with the usage of this method is that it does not provide any information on the magnitude involved in the measurements.

The main motive behind carrying out this research was to find out the new ways to make use of the methods that provide the facility of grouping the genes together on the basis of the similarity in their expression patterns and not to evaluate the methods that make grouping feasible which was duly accomplished.